• bc贷(中国区)官方网站

  • En

    • 科學研究

    科學研究

    以良藥求良效。

    • Contezolid can replace linezolid in a novel combination with bedaquiline and pretomanid in a murine model of tuberculosis
      Antimicrobial Agents and Chemotherapy / 2024
      View Publication
    • Preclinical toxicity evaluation of novel antibacterial contezolid acefosamil in rats and dogs
      J Appl Toxicol / 2024
      View Publication
    • Dose adjustment not required for contezolid in patients with moderate hepatic impairment based on pharmacokinetic/pharmacodynamic analysis
      Sec. Pharmacology of Infectious Diseases / 2023
      View Publication
    • In vivo pharmacodynamic study of contezolid acefosamil, a prodrug of contezolid for oral and intravenous administration
      Journal of Antimicrobial Chemotherapy / 2023
      View Publication
    • A phase I study of the safety, tolerability, and pharmacokinetics of contezolid acefosamil after intravenous and oral administration in healthy Chinese subjects
      Antimicrobial Agents and Chemotherapy / 2023
      View Publication
    • A Novel Leucyl-tRNA Synthetase Inhibitor, MRX-6038, Expresses Anti-Mycobacterium abscessus Activity In Vitro and In Vivo
      Antimicrobial Agents and Chemotherapy / 2022
      View Publication
    • Discovery of Antibacterial Contezolid Acefosamil: Innovative O-Acyl Phosphoramidate Prodrug for IV and Oral Therapies
      ACS Med. Chem. Lett. / 2022
      View Publication
    • Clinical Pharmacology and Utility of Contezolid in Chinese Patients with Complicated Skin and Soft-Tissue Infections
      Antimicrobial Agents and Chemotherapy / 2022
      View Publication
    • A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections
      Journal of Antimicrobial Chemotherapy / 2022
      View Publication
    • A Novel Oxazolidinone, Contezolid (MRX-I), Expresses Anti-Mycobacterium abscessus Activity In Vitro
      Antimicrobial Agents and Chemotherapy / 2021
      View Publication
    • Pharmacokinetics and Disposition of Contezolid in Humans: Resolution of a Disproportionate Human Metabolite for Clinical Development
      Antimicrobial Agents and Chemotherapy / 2021
      View Publication
    • Nonclinical Evaluation of Antibacterial Oxazolidinones Contezolid and Contezolid Acefosamil with Low Serotonergic Neurotoxicity
      Chem Res Toxicol / 2021
      View Publication
    1 2 3